The FDA recently reported new information showing a link between Actos side effects cancer problems and extended use of this medication. According to data from a multi-year study, there was an association between using Actos for longer than one year and an increased risk of Actos and bladder cancer.
• Discovering blood in your urine
• The need to urinate with greater frequency than normal
• An urgent feeling that you need to urinate
• Emptying your bladder while producing a small amount of urine
• Painful feelings while urinating
• Physical examination
• Urine tests: checking for blood in the urine and cancerous cells
• Cystoscopy: a thin tube, referred to as a “cystoscope” is inserted into your urethra and into the bladder
• Biopsy: a tissue sample is removed and a pathologist examines it looking for cancer cells
If a patient receives a diagnosis of bladder cancer, their treating physician will determine what stage the cancer is at in order to develop a treatment plan. This process is referred to as “staging”.
The bladder cancer stages include:
• Stage I: cancer cells (tumor) have spread deeper into the lining of the bladder, but have not grown into the muscle layer of the bladder.
• Stage II: the tumor has grown and spread into the muscle layers of the bladder.
• Stage III: the cancerous tumor continues to grow and spreads through the muscle layer and invades various tissues next to the bladder including the prostate, vagina, or uterus.
• Stage IV: the tumor has spread into the pelvic and abdominal walls, but cancerous cells are not found in the lymph nodes or cancer cells have invaded at least one nymph node or to other body parts that are not close to the bladder such as the lung or liver.
There are a number of test that your treating physician may order to diagnose which stage your cancer is at. These tests may include: blood tests; chest x-ray; IVP – a dye is injected into your blood vessels; CT scan; MRI; and ultrasound.
Actos Bladder Cancer Treatment Options
There are a number of different treatment approaches for patients diagnosed with Actos side effects bladder cancer. The type of treatment depends on several factors including: the location of the tumor in the bladder; whether the tumor has spread into the muscle layer or tissues found outside the bladder; whether the tumor has spread and it found in other areas of the body; the tumor’s grade; and the patient age and overall heath.
Surgery: There are several different surgical treatment options that your doctor may use depending on the stage of your bladder cancer and other health factors.
• Transurethral resection – this option is used during Stage I cancer and involves the surgeon using a cystoscope which is inserted into the bladder and treats the cancer through a combination of removing the cancer and burning away cancer cells using an electric current. Form most patients, this procedure presents few problems and can be repeated.
• Partial cystectomy – this surgery is for smaller tumors and involves removing the tumor, bladder tissue surrounding the tumor, and lymph nodes close to the tumor.
• Radical cystectomy – for patients diagnosed with Stage II or III bladder cancer where it has spread into the muscle layer, this procedure is used and the entire bladder is removed along with part of the urethra and nearby lymph nodes.
Chemotherapy: chemotherapy, which uses drugs to kill cancer cells, is used both before and after surgery depending on the individual patient’s circumstances. The drugs are administered in cycles with each treatment followed by a rest period.
Biological Therapy: this treatment option is used with patients early in their diagnosis. The therapy is a liquid which contains a form of weakened bacteria that is inserted into the bladder. The goal is for the bacteria solution to strengthen the body’s immune system and kill the bladder cancer cells.
Radiation Therapy: this course of treatment is usually used along with chemotherapy and uses high-energy rays to kill cancer cells that have invaded the muscle layer of the bladder.
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